C5 and C2

  • Data Source:
  • HPRD (in vitro)

C5

C2

Description complement C5 complement C2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 23455636 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Blood protein levels ( 29875488 28240269)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 29212778 30104761)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Early age-related macular degeneration ( 32843070)
  • Endometriosis ( 28881265)
  • Estimated glomerular filtration rate ( 31451708)
  • Estimated glomerular filtration rate in diabetes ( 31451708)
  • Hepatocellular carcinoma ( 21105107)
  • Inflammatory bowel disease ( 28067908)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Mosquito bite size ( 28199695)
  • Platelet aggregation ( 29185836)
  • Prostate cancer ( 23535732)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Systemic lupus erythematosus ( 24871463)
  • Ulcerative colitis ( 28067908)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 22 interacting genes: ANKS6 AQP6 C2 C3 C5AR1 C6 C7 C8B CPB2 CPLX4 CPN1 CREB3L1 EBP KEL KIR3DL3 LMNA MMGT1 NEMP1 PGRMC2 POU6F2 SSMEM1 VEZT 14 interacting genes: C3 C4B C5 CREB3 EBP ERGIC3 FAM209A MASP1 MUC1 PSMA4 SEC11C SLC10A1 SLC35C2 STOM
Entrez ID 727 717
HPRD ID 00405 08939
Ensembl ID ENSG00000106804 ENSG00000166278
Uniprot IDs P01031 Q59GS8 A0A0G2JL69 B4DQI1 B4DV48 P06681 Q53HP3 Q5JP69 Q8N6L6
PDB IDs 1CFA 1KJS 1XWE 3CU7 3HQA 3HQB 3KLS 3KM9 3PRX 3PVM 4A5W 4E0S 4P39 4UU9 5B4P 5B71 5HCC 5HCD 5HCE 5I5K 6H03 6H04 6RPT 2I6Q 2I6S 2ODP 2ODQ 3ERB
Enriched GO Terms of Interacting Partners?
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