TRPC1 and TRPC5

Data Source:
BioGRID (affinity chromatography technology, fluorescent resonance energy transfer)
HPRD (in vivo)

		TRPC1	TRPC5
Description		transient receptor potential cation channel subfamily C member 1	transient receptor potential cation channel subfamily C member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Receptor Complex	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Membrane Raft
	Molecular Function	Signaling Receptor Binding Cation Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity ATPase Binding Inositol 1,4,5 Trisphosphate Binding	Actin Binding Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Melanin Biosynthetic Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cytosolic Calcium Ion Concentration Response To Calcium Ion Calcium Ion Transmembrane Transport Regulation Of Cardiac Conduction	Calcium Ion Transport Manganese Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Peptidyl-threonine Phosphorylation Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Phosphatidylserine Exposure On Apoptotic Cell Surface Regulation Of Membrane Hyperpolarization
Pathways		TRP channels Role of second messengers in netrin-1 signaling Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS			Smoking behavior ( 19247474)
Interacting Genes		14 interacting genes: BMPR2 CAV1 GRIA1 HOMER1 HOMER3 ITPR2 ITPR3 MDFI MX1 PKD2 RHOA TRPC3 TRPC4 TRPC5	9 interacting genes: DRD2 ENKUR ITPR3 MX1 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4
Entrez ID		7220	7224
HPRD ID		11894	02273
Ensembl ID		ENSG00000144935	ENSG00000072315
Uniprot IDs		P48995	Q9UL62
PDB IDs
Enriched GO Terms of Interacting Partners?
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