TNFAIP1 and DAPP1

Data Source:
BioGRID (two hybrid)

		TNFAIP1	DAPP1
Description		TNF alpha induced protein 1	dual adaptor of phosphotyrosine and 3-phosphoinositides 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cul3-RING Ubiquitin Ligase Complex	Cytosol Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Identical Protein Binding	Protein Binding Phospholipid Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Apoptotic Process Immune Response Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Protein Homooligomerization	Protein Dephosphorylation Signal Transduction
Pathways			Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs			Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS		Blood protein levels ( 29875488) Low density lipoprotein cholesterol levels ( 29403010) Osteoprotegerin levels ( 25080503)	Red cell distribution width ( 32888494)
Interacting Genes		31 interacting genes: ARMC7 ARNT CAPN7 CARD9 CDC37 CSNK2B DAPP1 EPHA2 EPM2AIP1 EXOSC5 HAT1 HEXIM2 KCTD10 KCTD13 KDM1A LNX1 NTAQ1 NXF1 POLR1C PRKAG1 PSMA1 RHOA RHOB RIN3 SMARCB1 STK16 SUV39H1 SVIL TRIM54 ZDHHC17 ZMYND19	23 interacting genes: BTK CNDP2 ERBB3 FAIM FCHSD2 FXN GSTCD HSD3B7 HSPA1A LCK LYN MAP4K1 MGARP MYLIP PLAGL2 PLCG1 PLCG2 RBP7 RPL23 SRC TM4SF19 TNFAIP1 ZNHIT1
Entrez ID		7126	27071
HPRD ID		01856	05773
Ensembl ID		ENSG00000109079	ENSG00000070190
Uniprot IDs		Q13829	J3KNB3 Q9UN19
PDB IDs			1FAO 1FB8
Enriched GO Terms of Interacting Partners?
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