TFAM and TFB1M

Data Source:
HPRD (in vitro, in vivo)

		TFAM	TFB1M
Description		transcription factor A, mitochondrial	transcription factor B1, mitochondrial
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Protein-containing Complex Mitochondrial Nucleoid	Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Mitochondrial Promoter Sequence-specific DNA Binding Transcription Coactivator Binding Chromatin Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding DNA Binding, Bending Heat Shock Protein Binding Mitochondrial Transcription Factor Activity Sequence-specific DNA Binding	RRNA (adenine-N6,N6-)-dimethyltransferase Activity DNA Binding RNA Binding Protein Binding Mitochondrial Transcription Factor Activity
	Biological Process	Mitochondrial Transcription Transcription Initiation From Mitochondrial Promoter Mitochondrion Organization Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated	RRNA Modification Transcription Initiation From Mitochondrial Promoter Mitochondrion Organization RRNA Methylation
Pathways		Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis	Transcriptional activation of mitochondrial biogenesis rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Height ( 23456168) Metabolite levels ( 23823483) Midgestational circulating levels of PCBs ( 28235828) Refractive error ( 32231278)	Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Metabolite levels ( 23823483) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		10 interacting genes: AGTRAP ARL6IP1 COL8A2 MGST3 PNP STATH TECR TFB1M TFB2M TSPAN1	2 interacting genes: POLRMT TFAM
Entrez ID		7019	51106
HPRD ID		02702	09515
Ensembl ID		ENSG00000108064	ENSG00000029639
Uniprot IDs		E5KSU5 Q00059	E5KTM5 Q8WVM0
PDB IDs		3FGH 3TMM 3TQ6 4NNU 4NOD 6ERP 6ERQ 6HB4 6HC3	6AAX 6AJK
Enriched GO Terms of Interacting Partners?
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