BTG1 and RNF181

Data Source:
BioGRID (two hybrid)

		BTG1	RNF181
Description		BTG anti-proliferation factor 1	ring finger protein 181
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Cytoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Enzyme Binding Kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Cell Migration Negative Regulation Of Cell Growth Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Fibroblast Apoptotic Process	Protein Ubiquitination Protein Autoubiquitination
Pathways		FOXO-mediated transcription of cell cycle genes	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Heart failure ( 20445134) Metabolite levels ( 23823483) Schizophrenia ( 28991256 29483656 30285260)	Prostate cancer ( 21743467)
Interacting Genes		16 interacting genes: CCNA2 CDKN2D CNOT7 CNOT8 FADD GRB2 HOXB9 NCK2 PRMT1 RARA RNF181 SKP2 THRA THRB TUBA1A XRCC6	22 interacting genes: BCL10 BIRC2 BTG1 CARD11 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U VPS11 ZMYND10
Entrez ID		694	51255
HPRD ID		15912	14236
Ensembl ID		ENSG00000133639	ENSG00000168894
Uniprot IDs		P62324 Q6IBC8	Q9P0P0
PDB IDs
Enriched GO Terms of Interacting Partners?
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