TBXA2R and EMP1

Data Source:
BioGRID (two hybrid)

		TBXA2R	EMP1
Description		thromboxane A2 receptor	epithelial membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Integral Component Of Plasma Membrane Nuclear Speck	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Thromboxane A2 Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Positive Regulation Of Blood Coagulation Response To Testosterone Thromboxane A2 Signaling Pathway Response To Drug Response To Ethanol Positive Regulation Of Angiogenesis Positive Regulation Of Blood Pressure Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Catalytic Activity Cellular Response To Lipopolysaccharide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	Cell Death Epidermis Development Bleb Assembly
Pathways		Prostanoid ligand receptors G alpha (q) signalling events G alpha (12/13) signalling events Thromboxane signalling through TP receptor
Drugs		Ridogrel Seratrodast Morniflumate
Diseases
GWAS			Coronary artery calcification ( 23870195) Degraded stimulus continuous performance test score ( 31596458) Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Heel bone mineral density ( 30598549 28869591) Household income (MTAG) ( 31844048) Refractive error ( 32231278) Serum albumin level ( 29403010)
Interacting Genes		35 interacting genes: ADIPOR1 ARL6IP6 C5orf46 EMP1 GJB2 GNA11 GNA12 GNA13 GNAI2 GNAQ GNAS GNB1 GNG2 GPRASP1 GRK5 GRK6 MFSD5 MS4A13 NME2 NOX1 PRDX4 PRKCA PSMA7 PSME3 PTGIR RAB11A RACK1 RAF1 RPGRIP1L SLC35B4 SLC41A1 TM4SF4 VRK2 YWHAZ ZDHHC15	61 interacting genes: ANK1 ANKS6 APOL2 AQP6 ARL13B ARL6IP1 ASGR2 ATP6V0B ATP6V0E1 BTN2A2 CCR5 CD37 CD3G CD53 CD79A CEP70 CLDN9 CORIN CXCR2 EBP EDA EHHADH ERGIC3 FFAR2 GIMAP5 GPR42 GPRC5D HTR2C ISLR2 JPH1 KLRC1 LAPTM4B LEPROTL1 LHFPL5 LPAR6 LRRC3B LSMEM2 MAL MALL MS4A7 OPRM1 PLEKHB2 PMP22 RABAC1 RPRM SERTM1 SMIM3 SPACA1 STOM SYNE4 TBXA2R TEX264 TLCD4 TMEM114 TMEM160 TMEM218 TMEM239 TMEM262 TMEM31 TMEM9 TSPO2
Entrez ID		6915	2012
HPRD ID		01768	11892
Ensembl ID		ENSG00000006638	ENSG00000134531
Uniprot IDs		P21731 Q05C92 Q0VAB0	A0A024RAT0 P54849
PDB IDs		1LBN
Enriched GO Terms of Interacting Partners?
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