TAF7 and RBM6

Data Source:
BioGRID (two hybrid)

		TAF7	RBM6
Description		TATA-box binding protein associated factor 7	RNA binding motif protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding TFIIH-class Transcription Factor Complex Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Negative Regulation Of Histone H4 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	MRNA Splicing, Via Spliceosome RNA Processing
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278)	Age at first birth ( 27089180 27798627) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Height ( 28552196) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Menarche (age at onset) ( 21102462) Metabolic syndrome ( 31589552) Morning person ( 30696823) Platelet distribution width ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 30297969)
Interacting Genes		27 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	6 interacting genes: EEF1G MAPRE2 MIRLET7D MIRLET7G SF3B3 TAF7
Entrez ID		6879	10180
HPRD ID		07196	06054
Ensembl ID		ENSG00000178913	ENSG00000004534
Uniprot IDs		Q15545	A8K6Q4 E9PGM9 P78332
PDB IDs		4RGW 5FUR 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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