TAF4 and TAF10

Data Source:
HPRD (in vivo, in vitro)

		TAF4	TAF10
Description		TATA-box binding protein associated factor 4	TATA-box binding protein associated factor 10
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex MLL1 Complex	PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm STAGA Complex Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity	DNA Binding Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Enzyme Binding Estrogen Receptor Binding Identical Protein Binding RNA Polymerase Binding Promoter-specific Chromatin Binding
	Biological Process	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process Regulation Of Signal Transduction By P53 Class Mediator	G1/S Transition Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Regulation Of Gene Expression Histone Deubiquitination Protein Deubiquitination Cellular Protein-containing Complex Assembly Multicellular Organism Growth Histone H3 Acetylation Regulation Of DNA Binding Hepatocyte Differentiation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Body mass index ( 28892062) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Response to fenofibrate (LDL cholesterol levels) ( 27002377)	Malaria ( 31844061)
Interacting Genes		22 interacting genes: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 H3-4 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12	23 interacting genes: ATXN7 ESR1 FANCA FTL H3-4 POLR2A PSMC5 SETD7 SUPT7L TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6874	6881
HPRD ID		11797	15972
Ensembl ID		ENSG00000130699	ENSG00000166337
Uniprot IDs		O00268	Q12962
PDB IDs		1H3O 2P6V 6MZC 6MZD 6MZL 6MZM	2F69 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 4J7F 4J7I 4J83 4J8O 4WV4 5EG2 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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