SYN2 and SYN3

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SYN2	SYN3
Description		synapsin II	synapsin III
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Synaptic Vesicle Membrane SNARE Complex Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Synaptic Vesicle Postsynaptic Density Synaptic Vesicle Membrane Glutamatergic Synapse
	Molecular Function	ATP Binding Identical Protein Binding	ATP Binding
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Calcium-ion Regulated Exocytosis Synaptic Vesicle Clustering	Neurotransmitter Secretion Regulation Of Synaptic Transmission, GABAergic Synaptic Vesicle Clustering
Pathways		Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle	Serotonin Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Creatinine levels ( 29403010) Eosinophil counts ( 32888494) Estimated glomerular filtration rate ( 31152163) Fasting blood insulin (BMI interaction) ( 22581228) Glomerular filtration rate ( 29403010) Glycated hemoglobin levels ( 28898252) Heel bone mineral density ( 30598549) Height ( 28552196) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Leprosy ( 27976721) Platelet count ( 22139419 29403010) Thyroid stimulating hormone levels ( 32769997 25743335) Triglycerides ( 30275531) Type 2 diabetes ( 18372903) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385819) Alzheimer's disease progression score ( 29860282) Benign prostatic hyperplasia ( 30988330) Blood protein levels ( 29875488 28240269) Chronic obstructive pulmonary disease ( 30804561) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Heel bone mineral density ( 30598549) Height ( 21998595 20881960 25282103 25429064 31562340) Interleukin-6 levels ( 22205395) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Metabolite levels ( 23823483) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 31170924) Trunk fat mass adjusted for trunk lean mass ( 32239398)
Interacting Genes		7 interacting genes: CHRM4 NOS1AP PRKACA SYN1 SYN3 YWHAE YWHAZ	7 interacting genes: C9orf72 MORF4L1 MORF4L2 NOS1AP PIAS2 SYN1 SYN2
Entrez ID		6854	8224
HPRD ID		02857	04083
Ensembl ID		ENSG00000157152	ENSG00000185666
Uniprot IDs		B3KRB3 Q59GM1 Q86VA8 Q92777	A0A024R1I8 O14994 Q17R54 Q59EX7
PDB IDs			2P0A
Enriched GO Terms of Interacting Partners?
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