STX3 and CPLX2

Data Source:
HPRD (in vivo, in vitro)

		STX3	CPLX2
Description		syntaxin 3	complexin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Neuron Projection Presynaptic Active Zone Membrane Extracellular Exosome Schaffer Collateral - CA1 Synapse Postsynapse Glutamatergic Synapse	Nucleus Cytosol Dendrite SNARE Complex Terminal Bouton Perikaryon Calyx Of Held Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Postsynapse Glutamatergic Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding	SNARE Binding Protein Binding Syntaxin-1 Binding Calcium-dependent Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Population Proliferation Synaptic Vesicle Docking Cytokine-mediated Signaling Pathway Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation Regulation Of Neurotransmitter Secretion
Pathways		Other interleukin signaling
Drugs
Diseases
GWAS		High chromosomal aberration frequency (chromosome type) ( 31586183)	Age-related nuclear cataracts ( 24951543) Chronotype ( 30696823) Obesity-related traits ( 23251661)
Interacting Genes		52 interacting genes: AQP6 CD79A COQ9 CPLX2 CPLX4 CREB3L1 CYB561 DNAJC5 EBAG9 ELOVL4 ERGIC3 EVI5 FAM209A FXYD3 GPR152 GPX8 JAGN1 LMNA MANBAL MFSD14B MGST3 MMGT1 MSMO1 MTIF3 NAPB PGRMC2 REEP4 RMDN3 SCN3B SLC35C2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STX5 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TMEM14B TMPPE TMX2 TRPC3 TXLNA VAMP3 VAMP7 VAMP8 ZDHHC15	7 interacting genes: APP MYG1 NDRG4 PBX3 STX2 STX3 TSFM
Entrez ID		6809	10814
HPRD ID		15985	09234
Ensembl ID		ENSG00000166900	ENSG00000145920
Uniprot IDs		Q13277 Q53YE2	Q6PUV4
PDB IDs
Enriched GO Terms of Interacting Partners?
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