STAU1 and ADARB1

Data Source:
BioGRID (two hybrid)

		STAU1	ADARB1
Description		staufen double-stranded RNA binding protein 1	adenosine deaminase RNA specific B1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Microtubule Associated Complex Plasma Membrane Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Synapse
	Molecular Function	RNA Binding Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding	RNA Binding Double-stranded RNA Binding Double-stranded RNA Adenosine Deaminase Activity MRNA Binding Protein Binding TRNA-specific Adenosine Deaminase Activity Metal Ion Binding
	Biological Process	Viral Process Cellular Response To Oxidative Stress Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Modification Of Postsynaptic Structure Positive Regulation Of Long-term Synaptic Potentiation	Adenosine To Inosine Editing RNA Processing MRNA Processing Neuromuscular Synaptic Transmission Negative Regulation Of Cell Population Proliferation Base Conversion Or Substitution Editing Facial Nerve Morphogenesis Hypoglossal Nerve Morphogenesis Spinal Cord Ventral Commissure Morphogenesis Negative Regulation Of Cell Migration Multicellular Organism Growth Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Viral Genome Replication Innate Immune Response Neuromuscular Process Controlling Posture Defense Response To Virus Regulation Of Cell Cycle Innervation Muscle Tissue Morphogenesis Motor Behavior Motor Neuron Apoptotic Process
Pathways			C6 deamination of adenosine Formation of editosomes by ADAR proteins
Drugs
Diseases
GWAS		Anger ( 24489884) Change in quality of life in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Crohn's disease ( 32581322) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Height ( 28552196 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Waist circumference adjusted for body mass index ( 28552196)	Adult body size ( 32376654) Body mass index ( 28892062 25673413) HDL cholesterol levels ( 32203549) Logical memory (immediate recall) in mild cognitive impairment ( 29274321) Pulmonary function ( 17903307) Triglyceride levels ( 32203549) Type 2 diabetes ( 30130595)
Interacting Genes		44 interacting genes: ADARB1 APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NKRF NXT1 PABPC1 PABPN1 PPP1CA PPP1CC PRKRA RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 STRBP TAX1BP3 TINCR TUBB TUBB4A UBE2D3 UPF1 ZMAT3	54 interacting genes: APP EHHADH EIF2AK2 MIR1-1 MIR1-2 MIR106A MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A2 MIR19B2 MIR200A MIR200B MIR206 MIR221 MIR222 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F1 MIRLET7F2 MIRLET7G NKRF PIN1 PNPT1 PRKRA STAU1 STOX1 STRBP TARBP2 TCEANC UBE2I ZMAT4 ZNF346
Entrez ID		6780	104
HPRD ID		03422	06777
Ensembl ID		ENSG00000124214	ENSG00000197381
Uniprot IDs		B3KRE0 O95793 Q59F99 Q6PJX3	P78563
PDB IDs		4DKK 6HTU 6SDW 6SDY	1ZY7 5ED1 5ED2 5HP2 5HP3 6D06 6VFF
Enriched GO Terms of Interacting Partners?
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