STAT2 and IWS1

Data Source:
BioGRID (two hybrid)

		STAT2	IWS1
Description		signal transducer and activator of transcription 2	interacts with SUPT6H, CTD assembly factor 1
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol Plasma Membrane	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Ubiquitin-like Protein Ligase Binding	Protein Binding
	Biological Process	Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Defense Response Receptor Signaling Pathway Via JAK-STAT Viral Process Cytokine-mediated Signaling Pathway Regulation Of Cell Population Proliferation Response To Peptide Hormone Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Mitochondrial Fission	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation
Pathways		Interleukin-20 family signaling Interferon alpha/beta signaling Regulation of IFNA signaling Regulation of IFNA signaling Potential therapeutics for SARS	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Axial length ( 24144296) Height ( 20881960 25429064 23456168) Inflammatory skin disease ( 25574825) Lymphocyte percentage of white cells ( 32888494) Macular thickness ( 30535121) Psoriasis ( 25903422 25574825 23143594 19169254) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Refractive error ( 32231278)	Cardiac troponin-I levels ( 31014085)
Interacting Genes		22 interacting genes: AURKA CREBBP CXCR4 DOK4 EGFR EP300 FNTA GAA GSK3A GSK3B HDAC1 IFNAR1 IFNAR2 IRF9 IWS1 JAK1 JAK2 MED14 SMARCA4 STAT1 STAT6 TYK2	10 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1
Entrez ID		6773	55677
HPRD ID		02778	07639
Ensembl ID		ENSG00000170581	ENSG00000163166
Uniprot IDs		P52630 R9QE65	Q96ST2
PDB IDs		2KA4 6UX2 6WCZ	6EMR
Enriched GO Terms of Interacting Partners?
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