ST13 and CTRC

Data Source:
BioGRID (enzymatic study)

		ST13	CTRC
Description		ST13 Hsp70 interacting protein	chymotrypsin C
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GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome	Extracellular Region
	Molecular Function	Protein Binding Protein Domain Specific Binding Hsp70 Protein Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding DATP Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity Unfolded Protein Binding Chaperone Binding	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Protein Folding Response To Bacterium Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Protein Refolding Protein-containing Complex Assembly	Proteolysis Cellular Calcium Ion Homeostasis Cobalamin Metabolic Process
Pathways		Regulation of HSF1-mediated heat shock response	Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs
Diseases			Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Feeling nervous ( 29500382) Refractive error ( 32231278)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		20 interacting genes: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 HSP90AA1 HSPA1A HSPA1B HSPA4 HSPA8 NOS3 OLFM2 PSEN1 PTGER4 SMAD2 TTR VAV2	20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 ST13 TEX37 UBC VGLL3
Entrez ID		6767	11330
HPRD ID		08426	03242
Ensembl ID		ENSG00000100380	ENSG00000162438
Uniprot IDs		A0A140VKA6 B4E0U6 P50502 Q0IJ56	Q99895
PDB IDs		1UZS	4H4F
Enriched GO Terms of Interacting Partners?
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