SS18 and SMARCA4

  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro)

SS18

SMARCA4

Description SS18 subunit of BAF chromatin remodeling complex SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autoimmune thyroid disease ( 32581359)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Mean corpuscular hemoglobin ( 32888494)
  • Nickel levels ( 26025379)
  • Obesity-related traits ( 23251661)
  • Periodontitis (Mean PAL) ( 24024966)
  • QT interval (sulfonylurea treatment interaction) ( 27958378)
  • Rhegmatogenous retinal detachment ( 23585552)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Toenail selenium levels ( 25343990)
  • Adult body size ( 32376654)
  • Apolipoprotein B levels ( 32203549)
  • Coronary artery disease ( 32469254 24262325 30104761 33020668)
  • Coronary artery disease or ischemic stroke ( 24262325)
  • Coronary artery disease or large artery stroke ( 24262325)
  • Disorders of lipid metabolism ( 30166351)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Inflammatory skin disease ( 25574825)
  • Ischemic stroke ( 29531354)
  • LDL cholesterol ( 21347282)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 31969989)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Multiple sclerosis ( 31604244)
  • Response to statins (LDL cholesterol change) ( 31969989)
  • Stroke ( 29531354)
Interacting Genes 9 interacting genes: EP300 FUS GRB2 H3-3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4 80 interacting genes: ACTB ACTL6A AHR AR ARID1A ARID1B ARID2 BRCA1 BRWD1 CARM1 CBX5 CCNE1 CDK19 CDK8 CDKN2A CDX2 CEBPA CEBPB CHD4 CHFR CHMP5 CIITA CREB1 CTNNB1 E2F6 ESR1 ETS2 FANCA GATA1 GMNN H2AX H2BC21 H3-3A H3C1 H3C14 H4C6 HSF1 HSF4 HSPB1 IKZF1 KLF1 MBD3 MDM2 MED17 MED6 MPHOSPH6 MRTFA MYC MYOCD NR3C1 NR4A2 PABPN1 PALS2 PAX6 PBRM1 PHB PTEN RAP1A RASSF1 RB1 RBL1 RBL2 RELB RFXAP SIN3A SIN3B SMARCB1 SMARCC1 SMARCE1 SOX4 SS18 SS18L1 STAT2 STAT3 STK11 SUMO2 TAF15 TMF1 TP53 ZMYND11
Entrez ID 6760 6597
HPRD ID 02559 04459
Ensembl ID ENSG00000141380 ENSG00000127616
Uniprot IDs A0A024RC40 B4DLD3 B4DR34 B4E2J6 Q15532 Q4VAX0 A7E2E1 B3KNW7 P51532 Q9HBD4
PDB IDs 2GRC 2H60 3UVD 5DKD 5EA1 6BGH 6HR2 6LTH 6LTJ 6SY2 6ZS2
Enriched GO Terms of Interacting Partners?
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