BRDT and E2F6

Data Source:
BioGRID (two hybrid)

		BRDT	E2F6
Description		bromodomain testis associated	E2F transcription factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm MLL1 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Coactivator Activity Histone Binding Lysine-acetylated Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Histone Displacement Chromatin Remodeling Regulation Of Transcription, DNA-templated MRNA Processing Male Meiotic Nuclear Division Male Meiosis I Spermatogenesis RNA Splicing Cell Differentiation Regulation Of RNA Splicing Positive Regulation Of Transcription Involved In Meiotic Cell Cycle	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494)	Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Sudden cardiac arrest ( 21658281)
Interacting Genes		3 interacting genes: E2F6 H4C14 VAV2	27 interacting genes: APP ARAF BMI1 BRDT CENPU DNMT1 DNMT3L DNTTIP1 E2F1 EPC1 EZH1 EZH2 HMG20B INO80B KRTAP10-7 NFYA PCGF6 PIK3R3 RING1 RYBP SMARCA4 TFDP1 TFDP2 ZBTB17 ZBTB32 ZFPM2 ZMYND11
Entrez ID		676	1876
HPRD ID		03684	04251
Ensembl ID		ENSG00000137948	ENSG00000169016
Uniprot IDs		Q58F21	A0A0S2Z3K8 O75461 Q53YM3 Q6Q9Z5
PDB IDs		2RFJ 4FLP 4KCX 5VBQ 5VBR
Enriched GO Terms of Interacting Partners?
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