SPTAN1 and PTOV1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPTAN1	PTOV1
Description		spectrin alpha, non-erythrocytic 1	PTOV1 extended AT-hook containing adaptor protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Spectrin Microtubule Cytoskeleton Membrane Specific Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Extracellular Vesicle Tertiary Granule Lumen	Nucleoplasm Transcription Regulator Complex Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Cadherin Binding
	Biological Process	MAPK Cascade Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Neutrophil Degranulation Actin Filament Capping	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport
Drugs
Diseases		Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Axial length ( 24144296) Body mass index ( 26426971)
Interacting Genes		56 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB AKIP1 ANK1 CAPN1 CASP3 CASP7 CEP63 CTNNA1 DDX24 DES EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D KALRN KARS1 MAPK6 NEFL PDE4D PIN4 PLEC PLEKHA5 PRKCB PTEN PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SPTBN2 SPTBN4 SRC STAT1 SUMO2 SYN1 TAF1 TANC1 TES TSSC4 ZNF333	9 interacting genes: CCR4 DMTN HDAC6 PIN1 RACK1 SPTAN1 TMCC2 UBC USP16
Entrez ID		6709	53635
HPRD ID		01684	17929
Ensembl ID		ENSG00000197694	ENSG00000104960
Uniprot IDs		A0A384P5S9 Q13813	A0A0C4DGR2 Q86YD1
PDB IDs		2FOT 3F31 3FB2 5FW9 5FWB 5FWC 6ZEH
Enriched GO Terms of Interacting Partners?
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