SPINK1 and TMPRSS15

		SPINK1	TMPRSS15
Description		serine peptidase inhibitor Kazal type 1	transmembrane serine protease 15
Image
GO Annotations	Cellular Component	Extracellular Exosome	Brush Border Membrane Integral Component Of Membrane
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Nitric Oxide Mediated Signal Transduction Sperm Capacitation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Acrosome Reaction Negative Regulation Of Calcium Ion Import Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Store-operated Calcium Entry	Proteolysis Endocytosis
Pathways
Drugs
Diseases		Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis	Enterokinase deficiency
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Metabolite levels ( 23823483) Obesity-related traits ( 23251661)	Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)
Interacting Genes		6 interacting genes: ASPH CTRC ELN NRSN1 TMPRSS15 UBE3A	1 interacting genes: SPINK1
Entrez ID		6690	5651
HPRD ID		01341	05972
Ensembl ID		ENSG00000164266	ENSG00000154646
Uniprot IDs		P00995	P98073
PDB IDs		1CGI 1CGJ 1HPT	4DGJ 6ZOV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?