SNX1 and HCCS

Data Source:
BioGRID (two hybrid)

		SNX1	HCCS
Description		sorting nexin 1	holocytochrome c synthase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Holocytochrome-c Synthase Activity Protein Binding Heme Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis	Animal Organ Morphogenesis Cytochrome C-heme Linkage Protein Phosphopantetheinylation
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS			Cognitive performance ( 19734545)
Interacting Genes		48 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNX2 SNX32 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35	3 interacting genes: CIDEB SENP2 SNX1
Entrez ID		6642	3052
HPRD ID		03171	02085
Ensembl ID		ENSG00000028528	ENSG00000004961
Uniprot IDs		Q13596	A0A024RBY9 P53701
PDB IDs		2I4K 4FZS
Enriched GO Terms of Interacting Partners?
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