SNRPF and DDX20

Data Source:
HPRD (in vivo, in vitro)

		SNRPF	DDX20
Description		small nuclear ribonucleoprotein polypeptide F	DEAD-box helicase 20
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Sno(s)RNA-containing Ribonucleoprotein Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Repressing Transcription Factor Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Positive Regulation Of Apoptotic Process Import Into Nucleus
Pathways		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	snRNP Assembly
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560) Refractive error ( 32231278)	Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		26 interacting genes: COIL DDX20 GEMIN2 GEMIN5 GEMIN6 HOMER3 HSPB1 IKZF1 IL7R LNX1 LSM3 LSM5 LSM6 LSM7 MEOX2 OSBPL2 PSMA3 PUF60 RPL9 SMN2 SNRPD2 SNRPE SNRPG SRRT SRSF5 WDR77	32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		6636	11218
HPRD ID		04645	05859
Ensembl ID		ENSG00000139343	ENSG00000064703
Uniprot IDs		P62306	Q9H4N4 Q9UHI6
PDB IDs		3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P	2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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