POLR3D and POLR3E

Data Source:
HPRD (in vivo)

		POLR3D	POLR3E
Description		RNA polymerase III subunit D	RNA polymerase III subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity	DNA-directed 5'-3' RNA Polymerase Activity
	Biological Process	Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Transcription, DNA-templated Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Height ( 31562340) L-selectin levels ( 25576479)
Interacting Genes		13 interacting genes: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 POLR3E RBFOX2 RHOXF2 TAB1 ZNF496	2 interacting genes: POLR3A POLR3D
Entrez ID		661	55718
HPRD ID		01755	15155
Ensembl ID		ENSG00000168495	ENSG00000058600
Uniprot IDs		P05423	A0A0C4DH01 Q9NVU0
PDB IDs
Enriched GO Terms of Interacting Partners?
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