BOLL and POM121

Data Source:
BioGRID (two hybrid)

		BOLL	POM121
Description		boule homolog, RNA binding protein	POM121 transmembrane nucleoporin
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Cytoplasm Cytosol Plasma Membrane Flemming Body	Nuclear Envelope Nuclear Pore Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Nuclear Membrane Host Cell
	Molecular Function	MRNA 3'-UTR Binding Protein Binding Translation Activator Activity	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation Meiotic Cell Cycle 3'-UTR-mediated MRNA Stabilization	Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Asthma ( 31361310) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 18997786) Morning person ( 30696823) Rheumatoid arthritis ( 32868391) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Subcutaneous adipose tissue ( 22589738) Triglyceride levels ( 32203549)
Interacting Genes		37 interacting genes: AGRN ARID5A ATXN2L C1orf94 C4orf45 CBX2 DAZ1 DAZ4 DCANP1 EHHADH FAM168A FOXD4L1 HNRNPLL HYAL3 HYPK INO80B KRTAP19-3 NAF1 NPBWR2 PATZ1 PHF1 POGZ POM121 PRR34 RBFOX2 RBPMS RBPMS2 RHOXF2 SEMA3B SERF2 SNRPC SYCE1L TCEA2 TFG ZBTB32 ZC3H10 ZNF385C	42 interacting genes: AGR2 AP1B1 AP2B1 APC ATXN1 BOLL BRCA1 CCDC57 CEACAM6 CEP55 CEP76 CERT1 CLDN3 COG6 FAM168B FXR2 GFAP GOLGA2 GYG1 HOMER3 JMJD7 KPNA6 LPXN MAGED1 MORN5 NFKBIA OTUD6A PAXIP1 RBPMS SPAG5 STAT3 TEX11 TFIP11 TOX3 TRAF2 TRAF3 TRIM23 TRIM27 TRIM49 TRIP6 UBQLN2 ZMYND12
Entrez ID		66037	9883
HPRD ID		07314	11448
Ensembl ID		ENSG00000152430	ENSG00000196313
Uniprot IDs		Q8N9W6	Q96HA1
PDB IDs			5T6W
Enriched GO Terms of Interacting Partners?
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