SMARCC1 and STT3B

Data Source:
BioGRID (affinity chromatography technology)

		SMARCC1	STT3B
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	STT3 oligosaccharyltransferase complex catalytic subunit B
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GO Annotations	Cellular Component	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Protein-containing Complex Oligosaccharyltransferase I Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Protein N-linked Glycosylation Glycoprotein Catabolic Process Response To Unfolded Protein Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Co-translational Protein Modification Post-translational Protein Modification
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Periodontal disease-related phenotype (Socransky) ( 24347629) Urate levels ( 31578528)
Interacting Genes		53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581	1 interacting genes: INCA1
Entrez ID		6599	201595
HPRD ID		03435	12268
Ensembl ID		ENSG00000173473	ENSG00000163527
Uniprot IDs		Q58EY4 Q92922	Q8TCJ2
PDB IDs		2YUS 5GJK 6KZ7	6S7T
Enriched GO Terms of Interacting Partners?
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