SLC18A1 and MGAM

Data Source:
BioGRID (two hybrid)

		SLC18A1	MGAM
Description		solute carrier family 18 member A1	maltase-glucoamylase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Terminal Bouton Clathrin-sculpted Monoamine Transport Vesicle Membrane	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Serotonin:sodium Symporter Activity Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Catalytic Activity Glucan 1,4-alpha-glucosidase Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Alpha-1,4-glucosidase Activity Protein Binding Carbohydrate Binding Maltose Alpha-glucosidase Activity
	Biological Process	Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Xenobiotic Transport Serotonin Uptake Transmembrane Transport	Maltose Metabolic Process Starch Catabolic Process Neutrophil Degranulation Polysaccharide Digestion
Pathways		Na+/Cl- dependent neurotransmitter transporters	Digestion of dietary carbohydrate Neutrophil degranulation
Drugs		Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine	Acarbose Miglitol Voglibose
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cholesterol ( 31902109) Coronary artery disease ( 30104761) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertriglyceridemia ( 23505323) Major depressive disorder (broad) ( 20038947) Metabolic syndrome ( 30382898 31589552) Pulse pressure ( 27841878) Susceptibility to persistent hepatitis B virus infection ( 27244555) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Triglycerides ( 18193046 24886709)	1,5-anhydroglucitol levels ( 28588231) Anorexia nervosa ( 23568457) Blood metabolite levels ( 24816252) Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		60 interacting genes: AGTRAP ANKRD46 APOL2 BRICD5 C2CD2L CCL4 CCL4L2 CNIH1 COL4A5 CTSA CXCL16 CYB561D2 FAM3C FCER1G FXYD3 GIMAP1 GJB2 GPR151 LAT MALL MFSD6 MGAM MIP MS4A1 MS4A13 NEU1 NRM OLFM4 ORMDL1 PEX16 PLP1 PLP2 PMP22 PNLIPRP1 RPRM SLC30A2 SLC30A8 SLC35B4 SLC35G1 SLC38A7 SLC39A2 SMCO4 SMIM1 STX2 STX8 TFRC TMEM120B TMEM128 TMEM14A TMEM14B TMEM203 TMEM218 TMEM239 TMEM42 TMEM60 TMEM65 TMEM86A VAMP5 YIPF4 YIPF6	7 interacting genes: AQP6 CPLX4 CREB3L1 GPR42 NCF1 SLC18A1 TMEM14B
Entrez ID		6570	8972
HPRD ID		01897	01104
Ensembl ID		ENSG00000036565	ENSG00000257335
Uniprot IDs		P54219 Q96GL6	E7ER45 O43451
PDB IDs			2QLY 2QMJ 3CTT 3L4T 3L4U 3L4V 3L4W 3L4X 3L4Y 3L4Z 3TON 3TOP
Enriched GO Terms of Interacting Partners?
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