ZBTB8A and MCM10

Data Source:
BioGRID (two hybrid)

		ZBTB8A	MCM10
Description		zinc finger and BTB domain containing 8A	minichromosome maintenance 10 replication initiation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nucleus Nucleoplasm Nucleolus Replication Fork Protection Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Molecular_function Protein Binding Metal Ion Binding	DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding Enzyme Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication Initiation Cellular Response To DNA Damage Stimulus Cell Population Proliferation
Pathways			Activation of ATR in response to replication stress Activation of the pre-replicative complex
Drugs
Diseases
GWAS			Nicotine dependence symptom count ( 25555482)
Interacting Genes		76 interacting genes: ACOT12 AEN AP1M1 AP2M1 ARMC7 ARMCX1 BAZ2B BLK BYSL CBX8 CCDC33 CDC37 CDKL3 CEP70 CSNK1D CWF19L2 DDX6 DVL2 DVL3 EHHADH EIF1AD EP300 FAM161A FAM90A1 FXR2 GPATCH2L HIC2 JRK KAT5 KAT7 KIF5B KIF9 KIFC3 LGALS14 LMO3 LNX1 MCM10 MFAP1 MRPL11 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PRR34 PSMC1 RAD23A RPL9 SDCBP SYT6 TCEA2 TNIP3 TRIM41 UBE2I YES1 ZBTB17 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF329 ZNF35 ZNF408 ZNF417 ZNF438 ZNF497 ZNF572 ZNF587 ZNF648 ZNF837	38 interacting genes: APP CALCOCO2 CCDC85B CCND1 CCND3 CDC45 CDC5L CDC6 CDC7 CDK6 CDKN1A CDKN2A CEP70 CEP72 DAPK1 DPPA2 GOLGA2 HAUS1 HOOK2 IKBKG KLHL40 KRT15 MCM2 MCM3 MCM6 MCM7 NINL ORC2 ORC3 ORC4 PICK1 RECQL4 TNIP1 TRIM37 UBAC1 YWHAE ZBTB43 ZBTB8A
Entrez ID		653121	55388
HPRD ID		18902	11297
Ensembl ID		ENSG00000160062	ENSG00000065328
Uniprot IDs		D3DPQ1 Q96BR9	Q7L590
PDB IDs
Enriched GO Terms of Interacting Partners?
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