VPS33A and ROPN1

Data Source:
BioGRID (two hybrid)

		VPS33A	ROPN1
Description		VPS33A core subunit of CORVET and HOPS complexes	rhophilin associated tail protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Early Endosome Late Endosome Autophagosome AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Clathrin Complex	Nucleus Cytoplasm Motile Cilium
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome To Lysosome Transport Vesicle-mediated Transport Platelet Formation Melanosome Localization Lysosome Localization Regulation Of Lysosomal Lumen PH Regulation Of Developmental Pigmentation Autophagosome Maturation	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways			RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS			Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		7 interacting genes: MON1A MON1B ROPN1 TNKS VPS11 VPS16 VPS18	50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3
Entrez ID		65082	54763
HPRD ID		15651	15269
Ensembl ID		ENSG00000139719	ENSG00000065371
Uniprot IDs		Q96AX1	A0A140VKB2 Q9HAT0
PDB IDs		4BX8 4BX9
Enriched GO Terms of Interacting Partners?
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