ST3GAL3 and ZBTB5

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ST3GAL3	ZBTB5
Description		ST3 beta-galactoside alpha-2,3-sialyltransferase 3	zinc finger and BTB domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Protein Glycosylation O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256)	Bipolar disorder ( 31043756)
Interacting Genes		5 interacting genes: ACTG1 RPL8 SCAMP2 TTR ZBTB5	10 interacting genes: BAG4 CCDC85B DCX JADE2 METTL5 PPARG PTPN5 ST3GAL3 SWAP70 ZBTB7B
Entrez ID		6487	9925
HPRD ID		05930	08829
Ensembl ID		ENSG00000126091	ENSG00000168795
Uniprot IDs		A0A2R8Y732 Q11203	O15062 Q5T942
PDB IDs
Enriched GO Terms of Interacting Partners?
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