ST3GAL3 and KCNQ4

Data Source:
BioGRID (affinity chromatography technology)

		ST3GAL3	KCNQ4
Description		ST3 beta-galactoside alpha-2,3-sialyltransferase 3	potassium voltage-gated channel subfamily Q member 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Basal Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Protein Glycosylation O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation	Potassium Ion Transport Sensory Perception Of Sound Regulation Of Ion Transmembrane Transport Inner Ear Morphogenesis Potassium Ion Transmembrane Transport
Pathways		Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis	Voltage gated Potassium channels
Drugs			Enflurane Promethazine Miconazole Ezogabine ICA-105665
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)	Deafness, autosomal dominant
GWAS		Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		5 interacting genes: ACTG1 RPL8 SCAMP2 TTR ZBTB5	1 interacting genes: KCNQ3
Entrez ID		6487	9132
HPRD ID		05930	04641
Ensembl ID		ENSG00000126091	ENSG00000117013
Uniprot IDs		A0A2R8Y732 Q11203	B3KQH8 P56696
PDB IDs			2OVC 4GOW 6N5W
Enriched GO Terms of Interacting Partners?
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