ENGASE and ZP3

Data Source:
HPRD (in vitro)

		ENGASE	ZP3
Description		endo-beta-N-acetylglucosaminidase	zona pellucida glycoprotein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix Egg Coat Collagen-containing Extracellular Matrix
	Molecular Function	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Mannosyl-glycoprotein Endo-beta-N-acetylglucosaminidase Activity	Extracellular Matrix Structural Constituent Protein Binding Carbohydrate Binding Acrosin Binding Structural Constituent Of Egg Coat Identical Protein Binding Receptor Ligand Activity
	Biological Process	Protein Folding Protein Deglycosylation	Positive Regulation Of Type IV Hypersensitivity Blastocyst Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Leukocyte Migration Positive Regulation Of Humoral Immune Response Binding Of Sperm To Zona Pellucida Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-4 Production Egg Coat Formation Positive Regulation Of T Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Phosphatidylinositol-mediated Signaling Oocyte Development Positive Regulation Of Inflammatory Response Positive Regulation Of Acrosome Reaction Negative Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Antral Ovarian Follicle Growth
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Interaction With Cumulus Cells And The Zona Pellucida
Drugs
Diseases
GWAS			Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		1 interacting genes: ZP3	11 interacting genes: ACR CLDN11 ENGASE FURIN MALL MICALL1 MRPS16 OR2L13 PCDH17 SPACA3 UBAP2L
Entrez ID		64772	7784
HPRD ID		10978	01690
Ensembl ID		ENSG00000167280	ENSG00000188372
Uniprot IDs		Q8NFI3	P21754
PDB IDs
Enriched GO Terms of Interacting Partners?
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