SHC1 and AXL

  • Data Source:
  • HPRD (in vitro)

SHC1

AXL

Description SHC adaptor protein 1 AXL receptor tyrosine kinase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 143 interacting genes: ALK AP2A1 AP2A2 APP AR AXL BCL3 BCR BUB1 C11orf58 CALCOCO2 CALD1 CBL CBLB CBLC CD22 CD247 CD3E CD81 CDH5 CEACAM1 CRK CRKL CSF1R CSF2RB CSF3R CSK DAG1 DDR1 DDR2 DOK1 DUSP23 EGFR EPHA2 EPOR EPS8 ERBB2 ERBB3 ERBB4 ESR1 FAM118B FBXW7 FCGR2A FCGR3A FGFR1 FGFR2 FLT1 FLT4 FYN GAB1 GAB2 GEMIN7 GH1 GHR GRAP GRAP2 GRB2 GRB7 HMOX2 IGF1R IL2 IL2RB IL2RG IL4R IL6ST ILK INPP5D INPPL1 INSR IRS1 IRS2 ITGB3 ITGB4 JAK2 KDR KIT KRT18 LCK LCP2 LRP1 LTK LYN MAP4K1 MAPK1 MAPK14 MAPK6 MAPK8 MAPKAPK2 MET MME MPL MRPL44 MST1R NGFR NPM1 NTRK1 NTRK2 NTRK3 NUDT21 OSGEP PAG1 PAK1 PDGFRB PIK3C2B PIK3R1 PIK3R2 PLCG1 PLCG2 PLPP3 PLSCR1 PPP2R5A PRKCA PRKCD PRKRA PTK2 PTK2B PTPN11 PTPN12 PTPN2 PTPN6 RAPGEF1 RASA1 RB1 RET SH2B2 SHCBP1 SMAD4 SOS1 SOS2 SP1 SRC STAT5A STAT5B SUV39H2 SYK TEC TEK TPR TRIM15 UBASH3B VAV1 VAV3 ZAP70 23 interacting genes: ADAM10 CBL EGFR FBXO25 GAS6 GRB2 IL15RA IL2RG LCK MTDH NCK2 PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 RANBP9 SHC1 SHC3 SOCS1 SRC TNS2 TYRO3
Entrez ID 6464 558
HPRD ID 02780 00171
Ensembl ID ENSG00000160691 ENSG00000167601
Uniprot IDs P29353 M0R0W6 P30530
PDB IDs 1MIL 1N3H 1OY2 1QG1 1SHC 1TCE 1WCP 2L1C 4JMH 4XWX 5CZI 6DM4 2C5D 4RA0 5U6B 5VXZ
Enriched GO Terms of Interacting Partners?
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