GIGYF1 and RBM22

Data Source:
BioGRID (two hybrid)

		GIGYF1	RBM22
Description		GRB10 interacting GYF protein 1	RNA binding motif protein 22
Image		No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Prp19 Complex Nucleus Nucleoplasm Cytoplasm U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding Pre-mRNA Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Biological_process	MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Cellular Response To Drug Positive Regulation Of Protein Import Into Nucleus MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Protein Export From Nucleus
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		36 interacting genes: ANKRD10 ARMC7 ATN1 C1orf109 CBX8 CCDC57 CNOT9 CRACR2A DDX6 EIF4E2 ENKD1 FAM124B GRB10 GRB14 GRB7 KAT5 KIFC3 MCRS1 MNS1 NEK6 NFKBID PRKAA2 PRR35 RBM22 SCAF8 SCNM1 SMARCD1 SNRPA SNRPB SNRPC SPAG8 STAC3 TCEA2 TLE5 TROAP TSHZ2	14 interacting genes: AQR CEP55 CYSRT1 GIGYF1 GOLGA2 HNRNPUL1 HOMER3 NCKIPSD PRNP RBFOX2 RBM4 RNU6-1 RNU6-50P RNU6-6P
Entrez ID		64599	55696
HPRD ID		10145	10186
Ensembl ID		ENSG00000146830	ENSG00000086589
Uniprot IDs			Q9NW64
PDB IDs			2YTC 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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