MOSPD3 and TMPRSS2

Data Source:
BioGRID (two hybrid)

		MOSPD3	TMPRSS2
Description		motile sperm domain containing 3	transmembrane serine protease 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding FFAT Motif Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Heart Development Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Membrane Organization	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell
Pathways			Attachment and Entry Attachment and Entry Attachment and Entry
Drugs			Camostat
Diseases			Prostate cancer
GWAS		High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 28017375) Mean reticulocyte volume ( 32888494) Red blood cell count ( 28453575)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Prostate cancer ( 25217961)
Interacting Genes		17 interacting genes: ARL13B ATP5PF CD79A FATE1 FNDC9 GPR152 HSD17B13 IER3IP1 KASH5 MFF MILR1 PSCA REEP4 RETREG3 RILPL1 SAR1A TMPRSS2	59 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF UPK2 VAMP5 ZFPL1
Entrez ID		64598	7113
HPRD ID		12370	03637
Ensembl ID		ENSG00000106330	ENSG00000184012
Uniprot IDs		O75425	O15393
PDB IDs
Enriched GO Terms of Interacting Partners?
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