ROBO3 and CCDC57

Data Source:
BioGRID (two hybrid, two hybrid)

		ROBO3	CCDC57
Description		roundabout guidance receptor 3	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Axon	Centrosome Centriole Spindle Microtubule Centriolar Satellite
	Molecular Function	Protein Binding Cell-cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Axon Midline Choice Point Recognition Chemoattraction Of Axon Dendrite Self-avoidance Commissural Neuron Axon Guidance	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Macular thickness ( 30535121)	Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: APP CCDC57 CXCL14 HSF2BP LNX1 MTUS2 NEDD4L PICK1 RBMX	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 C2CD6 C4orf45 C9orf24 CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PPP1R32 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		64221	284001
HPRD ID		10554	14150
Ensembl ID		ENSG00000154134	ENSG00000176155
Uniprot IDs		F5GWJ5 Q96MS0	A0A590UJT6 Q2TAC2
PDB IDs		6POG 6POK 6POL
Enriched GO Terms of Interacting Partners?
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