LIN7B and DNAH1

Data Source:
BioGRID (biochemical)

		LIN7B	DNAH1
Description		lin-7 homolog B, crumbs cell polarity complex component	dynein axonemal heavy chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Axonemal Dynein Complex Microtubule Axoneme Dynein Complex Sperm Flagellum Inner Dynein Arm
	Molecular Function	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Microtubule Motor Activity ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Cilium Movement Microtubule-based Movement Sperm Axoneme Assembly Flagellated Sperm Motility Inner Dynein Arm Assembly Cilium-dependent Cell Motility
Pathways		Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronotype ( 30696823) Electroencephalogram traits ( 25387704) HDL cholesterol ( 30275531) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes		22 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12
Entrez ID		64130	25981
HPRD ID		10040	11790
Ensembl ID		ENSG00000104863	ENSG00000114841
Uniprot IDs		Q9HAP6	A0A140VJI6 Q9P2D7
PDB IDs		2DKR
Enriched GO Terms of Interacting Partners?
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