PKNOX2 and FAM110B

Data Source:
BioGRID (two hybrid)

		PKNOX2	FAM110B
Description		PBX/knotted 1 homeobox 2	family with sequence similarity 110 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge	Mitochondrion Microtubule Organizing Center Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Protein Binding Actin Filament Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)	Bipolar disorder and schizophrenia ( 20889312) Blood pressure measurement (low sodium intervention) ( 24165912) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Pit-and-Fissure caries ( 24556642) Shingles ( 30298529) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		32 interacting genes: ARFIP2 C10orf88 C1orf216 CCDC116 CCDC185 CCDC196 CENPP CREBL2 CSTF2T CTTNBP2 CTTNBP2NL DDA1 ENKD1 FAM110B FHL2 HGS HOXB1 IQGAP1 MBD3 MCRS1 MYO15B NRIP1 NUP54 NUP58 PBX4 PICK1 SMARCD1 STK16 TRIB3 TSG101 USHBP1 VPS37C	5 interacting genes: HSF2BP MEIS3 PKNOX1 PKNOX2 RHOU
Entrez ID		63876	90362
HPRD ID		17857	14609
Ensembl ID		ENSG00000165495	ENSG00000169122
Uniprot IDs		Q96KN3	A0A024R7V5 B3KRT5 Q8TC76
PDB IDs
Enriched GO Terms of Interacting Partners?
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