CCL8 and CXCL17

Data Source:
BioGRID (pull down)

		CCL8	CXCL17
Description		C-C motif chemokine ligand 8	C-X-C motif chemokine ligand 17
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Protein Kinase Activity Protein Binding Chemokine Activity Heparin Binding Phospholipase Activator Activity CCR Chemokine Receptor Binding	Protein Binding
	Biological Process	Monocyte Chemotaxis Positive Regulation Of Leukocyte Migration Protein Phosphorylation Calcium Ion Transport Cellular Calcium Ion Homeostasis Exocytosis Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Genome Replication Eosinophil Chemotaxis Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Leukocyte Proliferation Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Activation Of MAPK Activity Angiogenesis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of Monocyte Chemotaxis
Pathways
Drugs		Pidolic acid
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Crohn's disease ( 22412388)
Interacting Genes		20 interacting genes: ACKR1 ACKR2 ACKR4 CCL11 CCL13 CCL2 CCL26 CCR1 CCR3 CCR5 CXCL10 CXCL11 CXCL17 CXCL2 CXCL6 CXCL8 MMP3 PPBP VCAN XCL2	16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2
Entrez ID		6355	284340
HPRD ID		03791	18264
Ensembl ID		ENSG00000108700	ENSG00000189377
Uniprot IDs		P80075	Q6UXB2
PDB IDs		1ESR
Enriched GO Terms of Interacting Partners?
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