SCNN1G and SCNN1D

Data Source:
HPRD (in vivo)

		SCNN1G	SCNN1D
Description		sodium channel epithelial 1 subunit gamma	sodium channel epithelial 1 subunit delta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex	Plasma Membrane Integral Component Of Plasma Membrane Actin Cytoskeleton Membrane Sodium Channel Complex
	Molecular Function	Ion Channel Activity Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding Ligand-gated Sodium Channel Activity
	Biological Process	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Sodium Ion Homeostasis Cellular Response To Aldosterone	Sodium Ion Transport Ion Transmembrane Transport Sodium Ion Transmembrane Transport Response To Stimulus Sensory Perception Of Taste
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases		Liddle syndrome Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Bronchiectasis with or without elevated sweat chloride
GWAS		Heel bone mineral density ( 30598549) Parent of origin effect on receptive language ability (paternal) ( 32635940)	Inflammatory bowel disease ( 28067908) Platelet count ( 24777453) Ulcerative colitis ( 28067908)
Interacting Genes		13 interacting genes: COMMD10 EPN1 MAPK1 NEDD4 NEDD4L SCNN1A SCNN1B SCNN1D SERP1 SOX4 STX1A USP10 WWP2	2 interacting genes: SCNN1B SCNN1G
Entrez ID		6340	6339
HPRD ID		02862	03209
Ensembl ID		ENSG00000166828	ENSG00000162572
Uniprot IDs		A5X2V1 P51170	P51172
PDB IDs		6BQN 6WTH
Enriched GO Terms of Interacting Partners?
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