SCN2A and ANK3

  • Data Source:
  • HPRD (in vivo)

SCN2A

ANK3

Description sodium voltage-gated channel alpha subunit 2 ankyrin 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Bipolar disorder ( 22182935 21926972 18711365 24618891 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronotype ( 30696823)
  • Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Heel bone mineral density ( 30598549)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
  • Psychotic experience ( 31553412)
  • Refractive error ( 32231278)
  • Schizophrenia ( 20185149)
  • Third ventricle volume ( 31530798)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
Interacting Genes 5 interacting genes: ANK3 ARHGEF10L MPP3 RNF130 SCN4B 18 interacting genes: FADD FAS GABARAP HOOK1 KCNC1 MAP1LC3A MAP1LC3C MAPK6 NAB2 PIK3R1 PLEC SCN1B SCN2A SCNN1B SMAD2 SMAD3 SPTBN4 SRPK2
Entrez ID 6326 288
HPRD ID 03133 02715
Ensembl ID ENSG00000136531 ENSG00000151150
Uniprot IDs Q99250 Q12955 Q8NAK2
PDB IDs 2KAV 4JPZ 4RLY 6BUT 6J8E 4O6X
Enriched GO Terms of Interacting Partners?
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