RRBP1 and PRKD2

Data Source:
BioGRID (two hybrid)

		RRBP1	PRKD2
Description		ribosome binding protein 1	protein kinase D2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Ribosome Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane
	Molecular Function	RNA Binding Signaling Receptor Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium-dependent Protein Kinase C Activity Protein Kinase C Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Translation Protein Transport	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Adaptive Immune Response Protein Phosphorylation Cell Adhesion Cell Death Positive Regulation Of Endothelial Cell Migration Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Sphingolipid Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Protein Kinase D Signaling Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis
Pathways			Sphingolipid de novo biosynthesis
Drugs		Radezolid
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Frontotemporal dementia (age at onset) ( 29724592) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) HDL cholesterol levels ( 32203549) Height ( 31562340) Platelet count ( 32888494) Plateletcrit ( 32888494)	Chronic lymphocytic leukemia ( 18758461 28165464) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Heel bone mineral density ( 30598549) Post bronchodilator FEV1 ( 26634245) Primary sclerosing cholangitis ( 23603763 27992413)
Interacting Genes		4 interacting genes: ATF7IP KIF5B PRKD2 SMAD9	17 interacting genes: CASK DST GLRX3 GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2
Entrez ID		6238	25865
HPRD ID		11796	09523
Ensembl ID		ENSG00000125844	ENSG00000105287
Uniprot IDs		Q9P2E9	Q9BZL6
PDB IDs			2COA 3BGM 4NNX 4NNY
Enriched GO Terms of Interacting Partners?
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