RPS14 and KRR1

Data Source:
BioGRID (two hybrid)

		RPS14	KRR1
Description		ribosomal protein S14	KRR1 small subunit processome component homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome	Nucleoplasm Chromosome Nucleolus Cytoplasm Membrane Small-subunit Processome Intercellular Bridge
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding	RNA Binding Protein Binding
	Biological Process	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Erythrocyte Differentiation Maturation Of SSU-rRNA	RRNA Processing
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Atrial fibrillation ( 29892015) Blood trace element (Cu levels) ( 23720494) Blood urea nitrogen levels ( 29403010) Creatinine levels ( 29403010) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Polycystic ovary syndrome ( 30566500 26416764) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		10 interacting genes: APP CALM1 DUX4 KRR1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33	3 interacting genes: EWSR1 RPS14 SRPK1
Entrez ID		6208	11103
HPRD ID		00562	11027
Ensembl ID		ENSG00000164587	ENSG00000111615
Uniprot IDs		P62263	Q13601
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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