RPS13 and PDCD4

Data Source:
HPRD (in vitro, two hybrid)

		RPS13	PDCD4
Description		ribosomal protein S13	programmed cell death 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Negative Regulation Of RNA Splicing	Apoptotic Process Cell Aging BMP Signaling Pathway Interleukin-12-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development Cellular Response To Lipopolysaccharide Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Myofibroblast Differentiation Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Artenimol
Diseases
GWAS		Body mass index ( 26426971) Smoking status (ever vs never smokers) ( 30643258)	Fish- and plant-related diet ( 32066663)
Interacting Genes		6 interacting genes: DUX4 MAP3K14 NFKB2 PDCD4 PTEN SPP1	16 interacting genes: APOE BTRC CSNK2A1 EIF4A2 EIF4A3 EIF4G1 IBTK LRRK1 PSEN1 PSEN2 RPL5 RPLP1 RPS13 RPS6KA1 SKP2 SUMO2
Entrez ID		6207	27250
HPRD ID		01604	10549
Ensembl ID		ENSG00000110700	ENSG00000150593
Uniprot IDs		P62277	B4DKX4 Q53EL6
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I	2GGF 2KZT 2RG8 2ZU6 3EIJ
Enriched GO Terms of Interacting Partners?
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