RPS8 and RPS4X

Data Source:
BioGRID (biochemical, pull down, biochemical, biochemical)

		RPS8	RPS4X
Description		ribosomal protein S8	ribosomal protein S4 X-linked
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome Ribonucleoprotein Complex	Nucleoplasm Cytosol Ribosome Polysome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Viral Transcription Response To Ethanol Positive Regulation Of Translation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Artenimol
Diseases
GWAS
Interacting Genes		7 interacting genes: CALM1 DLG2 DLG3 DUX4 NDRG1 RPS4X SIRPA	13 interacting genes: ARPC3 CAMK2D CTBP2 DUX4 HNRNPH3 MCM2 PTEN RPS15 RPS7 RPS8 SUMO2 TRIM55 TRIM63
Entrez ID		6202	6191
HPRD ID		15969	02427
Ensembl ID		ENSG00000142937	ENSG00000198034
Uniprot IDs		P62241 Q5JR94	B2R491 P62701
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I	4UG0 4V6X 5A2Q 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLI 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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