RPL22 and SURF6

Data Source:
BioGRID (two hybrid)

		RPL22	SURF6
Description		ribosomal protein L22	surfeit 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Exosome Presynapse Glutamatergic Synapse Ribonucleoprotein Complex	Granular Component Nucleoplasm Chromosome Nucleolus
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Heparin Binding Identical Protein Binding Translation Regulator Activity	DNA Binding RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Alpha-beta T Cell Differentiation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission	Ribosomal Large Subunit Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) TPE interval (resting) ( 32386560)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Coagulation factor levels ( 23267103) Epithelial ovarian cancer ( 25134534) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Malaria ( 31844061) Serum alkaline phosphatase levels ( 24094242) Tonsillectomy ( 27182965 28928442) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		23 interacting genes: AP2M1 BAG4 BEND7 CALM1 CDC42 CSE1L CT45A1 DDIT4L DUX4 FGF11 H2BC15 IL7R MAPK14 MDM2 NSFL1C PTEN SDCBP SDCBP2 SRPK2 STAC3 SURF6 THAP1 ZCCHC10	3 interacting genes: CSNK2A1 FAM9B RPL22
Entrez ID		6146	6838
HPRD ID		01602	01714
Ensembl ID		ENSG00000116251	ENSG00000148296
Uniprot IDs		P35268	O75683
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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