RPL21 and PIM2

Data Source:
HPRD (two hybrid)

		RPL21	PIM2
Description		ribosomal protein L21	Pim-2 proto-oncogene, serine/threonine kinase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit	Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Electrocardiographic traits ( 17903306) Estimated glomerular filtration rate ( 31451708)
Interacting Genes		5 interacting genes: DUX4 HNRNPA1 PIM2 PTEN VHL	15 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBXO7 GSK3B HNRNPH3 HSF1 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821
Entrez ID		6144	11040
HPRD ID		04700	02244
Ensembl ID		ENSG00000122026	ENSG00000102096
Uniprot IDs		P46778 Q6IAX2	A0A024QYW7 Q9P1W9
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	2IWI 4X7Q
Enriched GO Terms of Interacting Partners?
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