RORB and TSGA10IP

Data Source:
BioGRID (two hybrid)

		RORB	TSGA10IP
Description		RAR related orphan receptor B	testis specific 10 interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Cilium Photoreceptor Connecting Cilium Ciliary Basal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Melatonin Receptor Activity Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter G Protein-coupled Receptor Signaling Pathway Visual Perception Intracellular Receptor Signaling Pathway Amacrine Cell Differentiation Eye Photoreceptor Cell Development Regulation Of Circadian Rhythm Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinal Rod Cell Development Retinal Cone Cell Development Rhythmic Process Retina Development In Camera-type Eye Cellular Response To Retinoic Acid	Cilium Organization
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Alcohol consumption (drinks per week) ( 30643258) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Chronotype ( 30696823) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Refractive error ( 23396134 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Acne (severe) ( 24927181) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Severe influenza A (H1N1) infection ( 26379185) Urate levels ( 31578528)
Interacting Genes		36 interacting genes: ANKS1A CLOCK CRACR2A CSNK2B DELEC1 FBXO7 GAS2L2 KRTAP4-5 LCK LCOR MAP6 MED25 MID2 NCOA1 NCOA6 NME1 NME2 NPPA NRIP1 NRIP2 NSD1 PNRC1 PNRC2 PSMC4 PSMC5 RORC SCNM1 SMARCD1 SOGA1 TEKT5 TLE5 TNNI2 TSGA10IP UBE2I ZNF417 ZNF587	112 interacting genes: AKAP8L AMOTL2 AP1B1 ARHGEF9 BHLHB9 BICD2 BICDL2 BIRC7 BRCA1 C1orf109 CALCOCO2 CARD9 CAVIN1 CBY2 CCDC102B CCDC120 CCDC125 CCDC13 CCDC136 CCDC57 CCDC88B CDKN2D CDR2 CDR2L CEP63 CEP70 CIB1 CRACR2B CTAG1A CTAG1B CYSRT1 DMAP1 DYDC1 EFHC1 FCHSD2 FHL3 FRS3 FSD2 GAS8 GOLGA2 GOLGA6A GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF3 JAKMIP1 KANK2 KHDRBS3 KIFC3 KRT24 KRT36 KRT40 KRT86 KRTAP12-2 KRTAP6-2 LCA5L LDOC1 LIPE LMNB2 LMO2 LZTS1 MAGED1 MBD3L1 MDFI MEIS3 MEOX2 MIPOL1 MIS18A MKRN3 MSS51 MTUS2 NAB2 NCOA5 NUTM1 PARVG PDLIM7 PICK1 PRDM6 PRKAR1B PSTPIP1 RASGEF1B RBM4B RBPMS ROPN1 RORB RUNDC3A SAAL1 SORBS3 SPG21 SSX2IP STX11 STX1A TBC1D1 TEKT1 TFIP11 TLE5 TRAF2 TRAF4 TRIM27 TRIM5 TRIM50 TRIP6 TSC1 TTC23 TTC23L UHMK1 WWOX YES1 ZRANB1
Entrez ID		6096	254187
HPRD ID		09062	08147
Ensembl ID		ENSG00000198963	ENSG00000175513
Uniprot IDs		Q58EY0	Q3SY00
PDB IDs
Enriched GO Terms of Interacting Partners?
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