NIF3L1 and SNF8

Data Source:
HPRD (two hybrid)

		NIF3L1	SNF8
Description		NGG1 interacting factor 3 like 1	SNF8 subunit of ESCRT-II
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	ESCRT II Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Transcription Factor Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	24 interacting genes: ADORA1 AKAP9 CHMP6 CLP1 CT55 DVL2 ELL FANCL GLYCTK GOLGA2 KDM1A NIF3L1 PRMT6 RILP SMARCD1 SUOX SUV39H2 TRIM54 TSG101 TXLNA VAC14 VPS25 VPS36 YWHAE
Entrez ID		60491	11267
HPRD ID		10424	16847
Ensembl ID		ENSG00000196290	ENSG00000159210
Uniprot IDs		A0A024R3V5 A0A024R3V7 Q9GZT8	Q96H20
PDB IDs			2ZME 3CUQ
Enriched GO Terms of Interacting Partners?
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