RNASE2 and ABCE1

Data Source:
HPRD (in vitro, in vivo)

		RNASE2	ABCE1
Description		ribonuclease A family member 2	ATP binding cassette subfamily E member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Azurophil Granule Lumen Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane
	Molecular Function	Lipopolysaccharide Binding Nucleic Acid Binding Ribonuclease A Activity Ribonuclease Activity Protein Binding Lyase Activity	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity
	Biological Process	Innate Immune Response In Mucosa RNA Catabolic Process Chemotaxis Induction Of Bacterial Agglutination Neutrophil Degranulation Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus RNA Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity
Pathways		Neutrophil degranulation	OAS antiviral response Interferon alpha/beta signaling
Drugs		Adenosine 3',5'-diphosphate Adenosine-2'-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Crohn's disease ( 20570966)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: ABCE1 DLG2 YWHAQ	3 interacting genes: EIF3J RNASE2 RNASEL
Entrez ID		6036	6059
HPRD ID		00577	03132
Ensembl ID		ENSG00000169385	ENSG00000164163
Uniprot IDs		P10153 W0UV60	P61221
PDB IDs		1GQV 1HI2 1HI3 1HI4 1HI5 1K2A 2BEX 2BZZ 2C01 2C02 2C05 5E13	6ZME 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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