GRK1 and SNCB

Data Source:
BioGRID (enzymatic study)

		GRK1	SNCB
Description		G protein-coupled receptor kinase 1	synuclein beta
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Disc Membrane	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus
	Molecular Function	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity ATP Binding Rhodopsin Kinase Activity	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding
	Biological Process	Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Autophosphorylation	Chemical Synaptic Transmission Response To Metal Ion Dopamine Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Regulation Of Neuron Death
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	MTF1 activates gene expression
Drugs
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)	Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
GWAS
Interacting Genes		9 interacting genes: ADRB2 CALM1 CAV1 PDE6D RCVRN RHO SNCA SNCB SNCG	13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA
Entrez ID		6011	6620
HPRD ID		01585	03980
Ensembl ID		ENSG00000185974	ENSG00000074317
Uniprot IDs		Q15835	G4Y815 G4Y816 Q16143
PDB IDs		5AFP
Enriched GO Terms of Interacting Partners?
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