RGS4 and SDHC

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		RGS4	SDHC
Description		regulator of G protein signaling 4	succinate dehydrogenase complex subunit C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Protein-containing Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Integral Component Of Membrane Respiratory Chain Complex II
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding	Succinate Dehydrogenase Activity Protein Binding Electron Transfer Activity Heme Binding Metal Ion Binding
	Biological Process	Inactivation Of MAPK Activity Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Heart Rate Response To Cocaine Response To Morphine Positive Regulation Of GTPase Activity Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Actin Filament Organization Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Potassium Ion Transmembrane Transport Dorsal Root Ganglion Development Positive Regulation Of Excitatory Postsynaptic Potential	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Aerobic Respiration
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Response to fenofibrate (triglyceride levels) ( 27002377) Response to mTOR inhibitor (rapamycin) ( 24009623)	Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		13 interacting genes: CALM1 COPB1 COPB2 EGFR ERBB3 GABBR1 GNAI1 GNAI2 GNAO1 GNAQ KRIT1 PLCB1 PTAFR	3 interacting genes: ARHGDIA MDM2 XRCC6
Entrez ID		5999	6391
HPRD ID		03947	03878
Ensembl ID		ENSG00000117152	ENSG00000143252
Uniprot IDs		A0A024R909 P49798	A0A0S2Z4B7 A0A0S2Z4C9 Q99643
PDB IDs
Enriched GO Terms of Interacting Partners?
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