BCL2A1 and HRK

Data Source:
HPRD (in vitro)

		BCL2A1	HRK
Description		BCL2 related protein A1	harakiri, BCL2 interacting protein
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GO Annotations	Cellular Component	Mitochondrial Outer Membrane	Mitochondrion Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding	Protein Binding
	Biological Process	Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cerebral Cortex Development Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Apoptotic Process Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 29403010 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Primary sclerosing cholangitis ( 27992413) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 29403010)	Alzheimer's disease (age of onset) ( 22005931) Brain morphology (MOSTest) ( 32665545) Brain structure ( 22504417) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) HATA volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Hippocampal volume ( 28098162 22504421) Presubiculum volume ( 30279459) Presubiculum volume (corrected for total hippocampal volume) ( 30279459) Subcortical brain region volumes ( 25607358) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		18 interacting genes: APP BAD BAK1 BAX BBC3 BCL2L11 BID BIK BMF BOK CT45A1 FAM9B GRB2 GSK3B HRK NR4A1 PMAIP1 SLC9A3R1	7 interacting genes: BAD BCL2 BCL2A1 BCL2L1 BCL2L2 C1QBP MCL1
Entrez ID		597	8739
HPRD ID		03034	04581
Ensembl ID		ENSG00000140379	ENSG00000135116
Uniprot IDs		Q16548	O00198
PDB IDs		2VM6 3I1H 3MQP 4ZEQ 5UUK 5UUL 5UUP 5WHH 5WHI 6E3I 6E3J 6MBB 6MBC 6RJP 6VO4	2L58 2L5B 6XY4
Enriched GO Terms of Interacting Partners?
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