ARID4A and EID1

Data Source:
HPRD (in vivo, in vitro)

		ARID4A	EID1
Description		AT-rich interaction domain 4A	EP300 interacting inhibitor of differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Transcription Repressor Complex	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding	Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Regulator Activity Histone Acetyltransferase Binding
	Biological Process	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Spermatogenesis Histone H4-K20 Trimethylation Histone H3-K9 Trimethylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Erythrocyte Development Histone H3-K4 Trimethylation Establishment Of Sertoli Cell Barrier	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Cell Differentiation Regulation Of Histone Acetylation Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Alcohol consumption in current drinkers ( 28937693) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778 33020668) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Problematic alcohol use ( 32451486) Venous thromboembolism ( 31420334) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		15 interacting genes: BRMS1 CCNA2 CCNB1 CCND1 CCNE1 CDK1 CDK2 CDK4 EID1 H3C14 H4-16 HDAC1 HDAC2 HDAC3 SIN3A	18 interacting genes: ARID4A CREBBP EP300 H2AC8 H2BC3 H3C1 H4C1 KAT2A MDM2 NCOA2 NDN NR0B2 PCID2 PSEN2 RB1 TRIM27 UBE3A XRCC6
Entrez ID		5926	23741
HPRD ID		01575	06907
Ensembl ID		ENSG00000032219	ENSG00000255302
Uniprot IDs		A0A024R657 A0A024R680 A0A024R6A2 P29374 Q05CG0	Q9Y6B2
PDB IDs		2LCC 2MAM 2YRV 6BPH
Enriched GO Terms of Interacting Partners?
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